The disease itself forms via atherosclerosis, a condition defined by a build-up of plaque (or fatty deposits) within the arteries. This plaque build-up causes the arteries supplying the limbs (known as the peripheral arteries) to narrow and harden, thereby restricting blood flow to the limbs, .
Half of people with PAD do not experience any symptoms, however those that do may have symptoms including, :
The current standard of treatment includes lifestyle changes, prescription medication, and sometimes surgery.
For cholesterol control
For high blood pressure
For diabetes control
Insulin / antiglycaemic drugs
For blood clot prevention
acute limb ischaemia; or critical limb ischaemia, when in the chronic (longer term) and not acute stage